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Both collaborations are outcome-driven with a focus on continually improving their efficacy.
Prodrugs are being designed to favourably alter the therapeutic index of these agents by improving their efficacy and reducing toxicity.
Rather than using a "trick" to make a donor think they are more efficient, Ord says, charities should focus on improving their efficacy.
Here, we present our current view of the therapeutic potential of the death receptor ligands TNF, CD95L and TRAIL and of the progress made towards improving their efficacy by tumor targeting, use of gene therapy and genetic engineering.
Some basic steps are required to facilitate them in improving their efficacy and effectiveness.
Our review of international (CBD) and EU biodiversity policy showed numerous opportunities for the integration of evolutionary knowledge, with the realistic prospect of improving their efficacy.
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To this end researchers at Verdia, a subsidiary of Maxygen, have taken natural fungicidal, insecticidal and herbicide-detoxification genes and improved their efficacy up to a thousandfold.
Climate change responses employed by other sectors (for example, energy, agriculture, transportation) are creating new ecosystem stresses, but also can incorporate ecosystembased approaches to improve their efficacy.
Better understanding of inflammatory processes might help tailor such therapies more effectively and improve their efficacy.
Appropriate management of cytostatic drugs is paramount to improve their efficacy on tumor cells while minimizing their toxicity.
However, it necessitates the implementation of specific immunization strategies to improve their efficacy.
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