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Improving the strain accommodation through segmented cracks produced by laser-glazing and reducing the penetration of the molten V2O5 by laser-glazed layer are the major mechanisms for extending the lifetime of the TBC.
In summary, the protein production improvements of the T. reesei TU6-vgb+ transformants shown in our study demonstrated that VHb was conducive to improving the strain's adaptability to oxygen-limiting conditions in viscous fermentation medium.
Complementation of the I2-1 mutant with three additional copies of lndI gene resulted in 15-fold increase in LaE production in comparison to the wild-type strain 1912 [ 130], demonstrating the effectiveness of such an approach for improving the strain.
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Over the past years, process development and metabolic engineering approaches have been adopted to develop recombinant PHA production strains for improving the strains' ability to produce PHA, and for changing the PHA structures to obtain better thermal and mechanical properties.
Researchers are in progress to increase the pigment yield by improving the strains genetically, optimising the fermentation process and utilising cheap agro-industrial waste to reduce the production cost.
The successful attempts have been made to improve the strain through mutations.
This will improve the strain selection for further utilization and documentation.
Therefore, the key of the research is to improve the strain's proteinase activity and determine its properties.
Subsequently, we improved the strain by performing multiple-integration of pathway genes resulting in resveratrol production of 235.57±7.00 mg L−1.
Finally, we suggest further works required to improve the strain performance suitable for successful commercialization of fermentative succinic acid production.
However, to develop an economical process of 1,3-propanediol production, it would be necessary to improve the strain by a metabolic engineering approach.
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