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This will aid in improving the concordance between preoperative and final histological diagnosis and thus prevent over and under treatment.
In addition, our revision to the CDS intervention where we linked the risk assessment to the prophylaxis order set grid had the intended effect of improving the concordance between the users' risk assessments (i.e. what they said they would order) and the prophylaxis actually ordered.
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This improves the concordance between readers, and enables one to differentiate a simple improvement with the disappearance of a lesion, or decreased intensity of lesions that can be subjective, from a significant response that would qualify as PR.
The introduction of common IA-2βA unitsignificantlyly improved the concordance between laboratories, in spite of the use of different assay protocols or antigens.
Using these values, our filtering criteria moderately improve the concordance between the single-cell and 100-cell experiments in two of the datasets but dramatically improve (decrease) the weighted sum of squares.
Altogether, modified Gleason grading has generally improved the concordance between biopsy and radical prostatectomy Gleason score, associates better with pathologic parameters at radical prostatectomy, and is more predictive for biochemical recurrence as well as metastasis and disease-specific death.
As we hypothesized, the FAF can improve the concordance rates between raters.
We found that correcting for CpG content did not improve the concordance of methylation scoring between biological or technical replicates.
Counting of HER2 gene copies by FISH, chromogenic in situ hybridization (CISH), silver-enhanced in situ hybridization (SISH), or dual-color dual-hapten in situ hybridization (DDISH) would greatly improve the concordance of HER2 status between CNB and surgically resected specimens [ 30- 32].
The addition of PMS2 immunohistochemistry may have improved the low concordance between MSI-H and loss of MMR gene expression in multiple cancers (49%).
While sampling more individuals would quantitatively improve this estimate, the concordance between this and previous estimates suggests that the median value is unlikely to be qualitatively improved without a much larger sample.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com