Sentence examples for improving secretion from inspiring English sources

If mutant OLFs unfold in similarly cooperative transitions, thermal stabilization of the fully folded protein may be sufficient for preventing aggregation and improving secretion, and screening for candidate chaperone molecules would be based on thermal stability alone.

Furthermore, we demonstrated that the engineered intein dramatically improves secretion of scFv-intein fusion proteins from yeast and, since the secreted proteins are folded and active, the scFvs can be directly functionalized and site-specifically immobilized via EPL and click chemistry.

Using site-directed mutagenesis of native SGSH, we identified an improved secretion variant that also displayed enhanced uptake properties that were mannose-6-phosphate receptor independent.

Depolarization of the membrane with 50 mM K+ in the presence of high glucose did not significantly improve secretion.

This suggests that placing strong hydrophobic amino acid residues in the signal peptide are required for the secretion of a recombinant protein, but the composition of amino acids in the h-domain is more critical than merely increasing total hydrophobicity to improve secretion of recombinant proteins.

In order to improve secretion of recombinant proteins in E. coli expression systems, a number of heterologous signal peptides have been evaluated (Velaithan et al. 2014; Jonet et al. 2012; Ismail et al. 2011; Low et al. 2011; Nagano and Masuda 2014).

The results showed that M105I mutant had a dose-dependent inhibitory effect on exocytosis, whereas, in the same range of concentrations, the wild type protein could even improve secretion (Fig. 8A).

Prone positioning improves secretion drainage from the airways, relieving lung compression by the heart and abdomen.

We also demonstrated improved secretion clearance in patients during CLR that were unrelated to P&PD.

This technique may be associated with nebulization [ 29] and has the potential to improve secretion clearance [ 30].

Continuous rotation did increase secretion clearance compared with manual turning, but the addition of percussion did not further improve secretion removal.