Sentence examples for improving radiosensitivity from inspiring English sources

Therefore, survivin inhibition may be an attractive therapeutic target to overcome the radioresistance while, in addition, proper attention to CIN (centrosome number) is considered important for improving radiosensitivity in human glioma.

No reports have been published to test them in CaP-radioresistant (RR) cells as radiosensitizers to improve radiosensitivity so far.

Gene therapy also rises as new approach to improve radiosensitivity combining two or more targeting genes.

Pre-clinical studies of cancer cell lines reported that erythropoietin (EPO) enhanced cytotoxicity, enhanced anti-tumour immune responses, and improved radiosensitivity (Leyland-Jones, 2013).

Another possible reason, however, may be the improved radiosensitivity by HBO to large residual tumours as well as small residual tumours.

These results indicate that BEZ235 can greatly improve radiosensitivity and overcome radioresistance in CaP-RR cells through inhibiting the PI3K/Akt/mTOR signaling pathway associated with the downregulation of EMT/CSC expression.

To develop effective therapeutics to improve radiosensitivity, understanding the possible pathways of radioresistance involved and the effects of a combination of the PI3K/Akt/mTOR inhibitors with radiotherapy on prostate cancer (CaP) radioresistant cells is needed.

Neoadjuvant hormonal therapy could theoretically improve tumor control through 3 mechanisms: (1) Cytoreduction of tumor volume through apoptosis, (2) enhanced tumor cell kill because of radiation induced damage that leads to alternative pathways for apoptosis, or (3) improved radiosensitivity through reduced intra-tumoral hypoxia.

In the next step, we found that combination with dual inhibitors (BEZ235 and PI103) and 6 Gy RT can greatly repress tumor colony growth, induce more apoptosis and improve radiosensitivity compared with combination with dual inhibitors (BMK120 and Rapamycin) and 6 Gy RT (P<0.05).

Considerable effort has been focused on devising methods for manipulating tumour oxygenation and thereby improving tumour radiosensitivity.

Inclusion of GNPs to improve the radiosensitivity of prostate cancer is expected to offer additional normal tissue sparing effects and is a promising area of development.