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In future research, we plan to explore these methods for improving estimation of the mean and standard deviation.
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Moreover, in dose-finding trials where HbA1c cannot always be assumed to reach steady state, the ability to predict steady-state outcome based on early data would allow improved estimation of the dose response curve and thus provides a basis for improved dose selection in phase III trials.
Overall, the method is found to achieve a substantially improved estimation of the hidden effect signatures in the RNA-Seq transcriptome expression landscape compared to other available techniques.
It is shown that the JPS scheme improves estimation of the population proportion in a very wide range of settings as compared to simple random sampling (SRS).
Optimal experimental design and simultaneous estimation of velocities and thermocouple positions by the Gauss Markov method using prior (but uncertain) information on the thermocouple locations––allow for highly improved estimation of the longitudinal thermal dispersion coefficient.
An improved estimation of the value ξ= 2 originally proposed by Halpin and Tsai is given through a set of finite element analyses that consider randomly distributed unidirectional fibers for different volume fractions.
In order to improve estimation of the risk of severe hyperkalemia, several formulas were generated based on an arbitrarily set cutoff potassium level >6.0 mmol/l and different serum parameters.
Alternative estimation procedures such as Bayesian methods should be considered to improve estimation of the heterogeneity.
It could help to improve estimation of the impact of proposed prognostic features on the main endpoints in the trial.
For participants sero-converting during the study, a PCR was done on the last antibody negative blood sample to improve estimation of the timing of infection.
In particular, information regarding tobacco or alcohol use and HIV status would potentially improve estimation of the proportion of OPSCC caused by HPV alone.
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