Still, important progress has been made, notably in setting up the Consumer Financial Protection Bureau and bringing greater transparency to derivatives trading (including work to improve derivatives markets begun at the New York Fed under Timothy Geithner before he became Treasury secretary in early 2009).
Tryptanthrin, BII, and improved derivatives thereof have not been distributed on a commercial scale for application as antibacterial agents, and thus, they might represent attractive scaffolds for developing new antibacterials.
Improved derivatives of collagelin should be developed by further increasing the affinity of the molecule for collagen, and improving the labeling procedures.
To our knowledge, these sdAb represent the first recombinant antibodies specific for BoNT serotypes other than A, B or E [70], [71], [72], [73] and we hope these and future improved derivatives will facilitate increased biosecurity.
Cidofovir displays significant nephrotoxicity and limited bioavailability, and this has prompted the development of improved derivatives.
Optimization of its pharmaceutical properties could provide improved derivatives with greater benefit to breast cancer patients.
SLAC is a heavily modified and improved derivative of the Suzuki-Gojobori counting approach [ 42, 93] that maps changes in the phylogeny to estimate selection on a site-by-site basis.
Many of the new rules designed to make finance safer raising capital levels, improving transparency in derivatives markets—are vital.
A combined compact difference scheme is developed for non-periodic problems (called NCCD henceforth) that simultaneously evaluates first and second derivatives, improving an existing combined compact difference (CCD) scheme.
By combining rtTA2-M2 and an improved Dox derivative, 9TB-Dox, we have provided strong evidence for fast and robust gene activation in neurons when episomal Ptetbi modules had been introduced into the brain of our rtTA2-M2CaMK-2 mice (live GFP fluorescence, Fig. 4A).
