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The package includes novel methodology on (i) filtering, reducing false positives, and (ii) GC content correction, improving copy number profile quality, especially under great read coverage and high correlation between GC content and copy number.
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Jensen said some of the stolen pages were in a significantly better condition than those in Hakimzadeh's books, leaving him with what appeared to be a much improved copy.
Improved copy and pasting technology is also coming for iPad, iPhone, and Mac.
Of course, improved copy and paste, faster performance, and more detailed battery information are all in tow as part of the overarching Gingerbread update, but Motorola has baked in some goodies of its own, too.
The NTC discarded Ratnik's advice to build an improved copy of the battleship of 8880 LT, but did not present a definite alternative.
This plasmid harbors an improved copy of the tetO promoter in pALC2073 that ensures complete repression when non-induced and high expression when induced by anhydrotetracycline.
We hybridized DNA from LAU-Me275 to Illumina 1M SNP arrays and analyzed the signals using the OverUnder algorithm [16], which uses minor allele frequencies in heterozygous loci to improve copy number estimation.
The proposed normalization strategy, as well as the adaptive sample-specific level scaling, provides powerful and convenient means for improved copy number analysis using aCGH.
We recently demonstrated a high-density array for self-digitization of sample volumes that could be adapted for improved copy number resolution in this device.
Samples were run in triplicate and assays in sextuplicate, which generated high numbers of replicate data points allowing for improved copy number resolution to an extent not possible by conventional qPCR (Weaver et al., 2010; Whale et al., 2012).
Several methods have been described that estimate, and then correct for, tumor cellularity in SNP array data in order to improve copy number profiles [ 2– 5] or in DNA sequencing data for mutation calling [ 6].
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