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Interestingly, deletion of p53 alone is also able to partially induce pluripotent cells from mouse embryonic fibroblasts and improves induction of pluripotent cells in other conditions [72].
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There he built a number of improved induction coils, including one that was awarded a 50,000-franc prize in 1858 by Emperor Napoleon III.
The corrosion processes occurring on the surface of the Fe73.5Si13.5B9Nb3Cu1 alloy ribbon with the amorphous structures improve induction Bs.
Recently, we found that such "DC exhaustion" could be prevented by the presence of IL-4 and IFN-γ during the maturation of mouse DCs (type-1 polarization), resulting in improved induction of anti-tumor immunity in cancer.
Improved induction, activation, or functionality of TB-specific CD8+ T cells may enhance protective immunity against TB [18].
Our observations also suggest that combining intradermal and intramuscular vaccination routes might be a new approach to improve induction of cellular immunity and warrants further evaluation.
Recently also protocols containing 2 novel agents have been used to improve induction regimens for patients with multiple myeloma.
41 42 The immunisation schedule may also be varied to improve induction of mucosa homing T cell responses.
A combined modality of improved induction chemotherapy followed by allo-HSCT may change the outcome of ATLL, and future studies may better focus on improving induction chemotherapy to allow an eventual increase in the number of candidates for allo-HSCT.
Conversely, if a tumour retains the wt TP53 gene and PATZ1 is underexpressed, increasing the expression of PATZ1 could enhance p53 activity, thus improving induction of the apoptotic process.
Addition of a triphosphate to a different region of the genome did not improve induction, showing that sequence components other than the triphosphate group determine the extent of RIG-I activation (Saito et al. 2008).
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