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Including this information greatly impacts BRCAPRO carrier probabilities and improves distinction between BRCA1 and non- BRCA1 breast tumors.
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Further study in a larger cohort of these rare ovarian tumours through a multicentre collaboration would be useful to see whether there is a novel way of imaging to facilitate preoperative diagnosis and to improve distinction between benign from malignant struma ovarii.
Denaturation and annealing-extension temperature were optimised for each assay to improve distinction between positive and negative droplets (Additional file 1: Table S1).
Measurement of complexes between complement-activation products and joint-specific molecules might provide improved specificity to the diagnostics of RA and may give better distinction between patients with complement-mediated joint inflammation and healthy individuals.
But as surveillance technology improves, the distinction between public spaces and private spaces becomes less meaningful.
We demonstrate that a combination of different analytical approaches substantially improves the distinction between transient and cyclic gene expression.
To develop a new decision tree system (DTS) for the management of adnexal masses in prepubertal and adolescent girls, aimed to improve the distinction between benign and malignant masses, help preserve affected ovaries during surgery, and reduce the rate of surgical management of uncomplicated functional ovarian cysts.
Variation of the structure of the substrates, modification of the reaction system or protein engineering (e.g. the expression of pure enzymes, rational design or directed evolution) are strategies that can be employed to improve the distinction between two enantiomers or enantiotopic groups.
When applied in combination, CANTAB and language tests did not improve the distinction between subgroups.
Consequently, stratification by age groups and menopausal status might improve the distinction between healthy and diseased individuals.
Discourse analysis of this type would improve the distinction between facts, speculative statements, pre-existing and new work.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com