Protein C may be up-regulated by platelet factor 4. This cytokine is conjectured to improve activation of protein C by forming an electrostatic bridge from protein C's Gla domain to the glycosaminoglycan (GAG) domain of thrombomodulin, reducing the Michaelis constant (KM) for their reaction.
Improved activation of molecular mechanisms of salt adaptation may be seen in transgenic rice plants over-expressing SAPK4.
The combination of Tc and Th epitopes in the Tc-ErbB2/Th-HA liposomes was primarily intended to enhance the function of DCs and improve activation of CD8+ T-cells through the recruitment of CD4+ T-lymphocytes.
In view of the impaired protein C system present in many patients with PE, we hypothesized that treatment with DAA might lead to more effective anticoagulation and improved activation of fibrinolysis, compared to therapy with enoxaparin alone.
A clinician focusing on major trauma in the ambulance control room improves activation times of prehospital critical care teams.
By the way, the OECD had been urging the Irish authorities for about 15 years to undertake this amalgamation as a way of improving activation, and they had steadfastly ignored its advice until the crisis hit and Fas collapsed an example of the crisis producing at least one positive outcome!
Electrochemical studies show that Li3PO4 coating improves the activation of Mn4+ ions, prohibits the growth of solid electrolyte interface film and facilitates the charge transfer reactions at the electrode/electrolyte interface.
In addition, although the presence of iron has been suggested to improve the activation of NFS1 cysteine desulfurase activity by frataxin (Tsai and Barondeau, 2010), the metal is not required for the interaction between frataxin and the ISCU-NFS1-ISD11 complex (Schmucker et al., 2011).
Therefore, we improved the vaccination protocol by adding plasmid DNA-secreting GM-CSF to the Mage-b DNA vaccine, aiming to improve the activation of APCs, such as macrophages.
