Despite these improvements, sequence-based resources are still lacking for many non-model species such as marine mammals, hampering molecular understanding of unique adaptations and physiology.
Ortholog assignment between C. elegans and C. briggsae is further improved based on gene model improvement, sequence similarity, and synteny when applying our gene model improvement procedure.
The increasing availability of whole mitochondrial genomes due the improvement sequencing technologies, and the rising of phylogenomics may reduce this limitation in the next future.
In conjunction with improvements in sequence quality, the generation of long sequence reads (of 10,000 bases or longer) is another key factor for haplotype improvement [ 18, 19, 82].
With the rapidly evolving improvements in sequence analysis techniques, an enormous amount of intronic sequence variation, like intronic single-nucleotide polymorphisms (SNPs), are detected.
Results: We introduce here freeIbis, which offers significant improvements in sequence accuracy owing to the use of a novel multiclass support vector machine (SVM) algorithm.
Their formal description will provide the basis for improvements of sequence databases, antimicrobial susceptibility studies, and epidemiologic surveys to characterize their pathogenicity.
Hence it is possible that ELP/ CTI orthologues may be identified within these genomes with future improvements in sequence coverage and assemblies.
Recent advances in library preparation methods enable high-throughput next generation sequencing (NGS) and technological improvements in sequencing chemistries now offer sufficient read lengths to encompass STR alleles.
Next generation sequencing technologies have brought about great improvements in sequencing throughput and cost, but do not yet allow for de novo sequencing of large repetitive genomes as found in most crop plants.
The rapid improvements in sequencing technologies are adding new sequences to the databases faster than the pace at which insights into their function could be gained.
