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These quality-of-life improvements are consistent with the improvements in mood measured with the Beck Depression Inventory, the Cornell Dysthymia Rating Scale, and the Profile of Mood States among patients receiving lamotrigine.
Nonetheless, these improvements are consistent with the finding that leptin replacement tends to normalize certain brain structures in leptin deficient mice.
The improvements are consistent over the four testing datasets with respect to the major performance indicators.
The findings of the current study with regards to balance improvements are consistent with previous RCTs [ 15, 16].
These improvements are consistent with a recent meta-analysis by Hooper et al. (19), which indicated promising benefits of CFs on insulin sensitivity.
The associations of sex, insurance coverage, diabetes type, diabetes duration, and A1C at baseline with 12-month QOL improvements are consistent with previous studies examining changes in QOL after clinical or medical intervention (24, 25) and help to identify patients who may experience QOL fluctuations over time.
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These PRO improvements were consistent with the clinical effect of brodalumab of improved PASI, 17 suggesting that improvements in psoriasis symptoms may lead to improvements in HRQoL.
These improvements were consistent with the clinical benefits observed in golimumab-treated patients in this study.
Improvements were consistent for the 3- and 12-month time frames.
These improvements were consistent for both independence skills and social skills.
It is not clear why this occurred, however, the trends toward improvements were consistent with results in previous studies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com