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The 43 760 predicted protein-coding loci should be examined by further improvement of sequence assembly and gene prediction.
The improvement of sequence databases, including EST databases, and repeat databases will be instrumental in the successful design of these probes for cross-species hybridizations.
Our study not only provides essential information for the improvement of sequence assembly but also offers molecular tools for cucumber genomics research, comparative genomics and evolutionary study.
With the improvement of sequence coverage, sequence quality and mapping algorithms, in silico SNP detection will become increasingly reliable in the future.
This systematic approach for recognition of novel species with potential diagnostic or therapeutic relevance provides a basis for epidemiologic surveys and improvement of sequence databases and may lead to identification of new clinical entities.
The use of the web interface within the PubMLST Neisseria database enables a process of community annotation whereby different members of the community can participate in the maintenance and improvement of sequence annotation and interpretation.
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The rapid improvement of sequencing technologies has enabled a number of different sequencing-based applications like genome resequencing, RNA-Seq, ChIP-Seq and many others [ 2].
Besides, additional minor miRNAs (also called miRNA star) can be also detected with the improvement of sequencing depth.
The fields of genomics and transcriptomics maintain their fast development thanks to the improvement of sequencing technologies and associated bioinformatic tools for assembly and annotation.
This approach, together with continuing improvement of sequencing technology, allows medical genomics to be a routine diagnostic method for rare Mendelian disorders in the near future.
The subsequent improvement of sequencing technologies made feasible the metagenome shot-gun sequencing of environmental samples; however, most environmental communities are far too complex to be fully sequenced in this manner.
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