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This suggested that for pain, a minimally important improvement was a 10-20% decrease in pain intensity, a moderately important improvement a decrease of 30% or more, and a substantial improvement a decrease of 50% or more.
Similarly there was a trend in favour of the intervention arm when the scores were analysed as a binary variable in terms of improvement (a decrease of at least 50% from the baseline score) or recovery (values below 10).
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Disease activity showed improvement, with a decrease of ≥4 points in activity scores for eight of 15 evaluable patients.
Clinically important deterioration in health status was defined as an increase of ≥9.6 WOMAC units and improvement as a decrease of ≥8.2 WOMAC units [ 29].
The procedure led to UDVA and CDVA improvement and a decrease of the steep Sim K from 50.37 D to 44.21 D, as well as reduction of corneal asymmetry and spherical aberration.
We characterized an "improvement" as a decrease of over 20% in postoperative THI scores compared with the preoperative THI scores (Khedr et al. 2008) or a decrease of more than 2 THI score grades according to McCombe's (McCombe et al. 2001) classification (Table 1).
Upon normalization of serum testosterone there was an improvement of hyperglycemia, a decrease of leukocytes and of fibrinogen levels, an increase of antithrombin III activity and of tissue oxygen pressure.
Polyphenols also decrease graft failure after transplantation of ethanol-induced fatty livers and small-for-size rat livers, an improvement associated with a decrease of ESR detectable free radical production [ 19, 20].
Organ failure improvement was defined as a decrease of the SOFA score between day 3 and day 1 of the infection for which the beta-lactam was prescribed.
However, during therapy three patients with clinical improvement did not show a decrease of CSF total protein.
This can result in an oxygenation improvement, probably due to a decrease of 'true' shunt and/or a more homogeneous ventilation to perfusion ratio.
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