Sentence examples for improved transduction efficiency from inspiring English sources
The vector possessed a self-complementary genome for improved transduction efficiency, 49, 50 and codon optimization for improved efficiency of transgene expression.
Interestingly, our data also showed that higher cytokine concentrations do not provide for improved transduction efficiency over that achieved with just 10 ng/ml of SCF, Flt3L and TPO.
PEI has been used to deliver DNA plasmids with improved transduction efficiency [ 81, 136– 136].
The presence of a central DNA flap in lentiviral vectors improves transduction efficiency significantly.
Here we designed nanocomplexes of rAd particles coated with (1) the polyethylene glycol derivative APS to provide a hydrophilic surface that would prevent entrapment in the hydrophobic mucus, and (2) the cell-penetrating peptide TAT to improve transduction efficiency.
Although the effect on synovial cell proliferation was not strong, our results demonstrate that it is possible to inhibit synovial cell proliferation by selecting useful affibody clones and by improving transduction efficiency of affibody protein molecules.
Therefore, combination of Adv and AAV vectors not only reduces the side effects associated with Adv but also improves transduction efficiency of AAV.
Understanding the mechanisms underlying CPP-mediated cellular uptake and subcellular localization of the carrier system is needed to improve transduction efficiency and cargo functionality.
Briefly, AGS cells were incubated with the NET1-specific shRNA lentiviral particles at a ratio of 2 particles to 1 cell, in the presence of hexadimethrine bromide to improve transduction efficiency.
LE6 cells were incubated with Smad4-specific shRNA lentivirus particles at a ratio of 25 particles to 1 cell, in the presence of 8 μg/ml hexadimethrine bromide to improve transduction efficiency.
These appear to provide more reliable and rapid expansion of T cells and may therefore improve transduction efficiency and also generate higher numbers of cells that are needed for adoptive transfer.
