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"We've improved the assembly of our major sections.
The use of random sampling improved the assembly of the sequence data from the second-generation sequencers.
The manual clone-by-clone alignment and gene annotation as well as detailed repeat and SNP/haplotype analyses significantly improved the assembly of the human DEF 8p23.1 locus.
It has the advantage of providing the longest reads, simplifying the assembly of whole transcripts without a reference genome, even though new algorithms improved the assembly of shorter sequences as produced by other methods (Table 2).
Taudien and colleagues by manual clone-by-clone alignment significantly improved the assembly of defensin 8p23.1 locus, providing in silico evidences of the experimentally verified variability in defensin copy number and better representing the locus diversity [ 7].
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Optical mapping is an important technique that can provide long genomic linkage information in a high-throughput manner, which has substantially improved the assemblies of several important model plant genomes sequenced to date.
To increase the accuracy of our analysis, we improved the assemblies of the D. mojavensis and D. grimshawi F elements and the base of the D. mojavensis D element, closing 72 of 86 gaps and adding 44,468 bases to these assemblies.
Much effort has gone into improving the assembly of these types of regions and some progress has been made with assembling transposons using specific transposon-based approaches [ 26].
This article, in order to improve the assembly of the high-pressure spool, presents an assembly variation identification method achieved by response surface method (RSM -based M -baseddating using IV-optimodelesigns.
The use of reference genomes allows researchers to improve the assembly of the most abundant microbial species, but this approach is limited by the small subset of microbial phyla for which sequenced genomes are available.
DG analysis also helped improve the assembly of the sorghum reference genome sequence.
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