In addition to the pharmacokinetic and pharmacodynamic peculiarities, the preterm population is characterized by organ immaturity and specific pathological conditions (e.g. respiratory distress syndrome, PDA) [ 3], improving risk of drug-related injuries.
What remains uncertain, and may so remain for many years until REACH is fully implemented, is whether the promise of improved risk management of chemicals and improved environmental and public health will be realized.
The aim of improved risk assessment of asthma is to achieve optimal asthma management without delay in preschool children with symptoms suggestive of asthma who are at high risk of developing asthma.
Addition of urinary TIMP-2 or NAG significantly improved risk prediction of severe AKI when evaluated using continuous NRI and IDI.
Improved risk stratification of patients for TLS will be critical to optimizing the use of this unquestionably active agent.
The improved risk profile of banks' borrowers also means they will have better data to work with.
Category II fetal heart rate (FHR) tracings are considered indeterminate; thus, improved risk stratification of category II FHR tracings is needed.
Improved risk stratification of patients prior to therapy in addition to novel molecularly tailored drugs are therefore urgently needed to improve the prognosis of children with MB.
Understanding the molecular biology of ALL underlies development of improved risk stratification and new therapies.
