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These amounts reflect a 105% increase between 2003 and 2008 and improved prioritization of countries based on the burden of maternal and child deaths.
Today, these efforts result in an improved prioritization of interventions and an enhanced and more rational use of available resources", affirmed Ms. Marianne Flach, UNICEF Representative in the Republic of Congo.
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Realtime harnesses social graph characteristics to improve prioritization.
In this work, we test the hypothesis that random-walk analysis of the protein interactome can improve prioritization of candidate disease genes in exome sequencing studies.
Kichaev et al. [ 51] integrated functional annotation with genetic association data using an empirical Bayes prior to improve prioritization of causal variants in fine mapping studies.
Most common uses of text mining are applications to improve prioritization of relevant documents for curation, identification of evidence (especially from full text) and linking of entities and relations to biological resources, e.g. EntrezGene or GO.
Accordingly, pathway ontology annotations can serve to fill in this knowledge gap, helping to decide whether a gene is truly relevant to the query phenotype and improving prioritization accuracy by removing noise.
Strategies to prioritize candidate genes in exome sequencing studies can also exploit the variant data itself in an attempt to improve prioritization of Mendelian disease genes, somatic mutations in cancer and others.
Early diagnosis and management need to be improved, using prioritization tools for early reference and T2T and tight control strategies until remission or low disease activity are achieved.
In the latter case, although the method has not improved the prioritization of causal variants much, there is still useful information to be gained from the proportion of posterior probability assigned to each variant, especially if a few variants account for a large fraction.
Such findings suggest that some type of standardization might produce more precise and structured referrals that again would improve the prioritization processes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com