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This assumption also shows improved power of the CDR-sb over the ADAS-cog, specifically due to the improvement in sensitivity or signal to noise ratio.
These results demonstrate the feasibility and improved power of performing association testing using viral genetic variation as outcome, independent of clinical phenotype.> -wrap-foot> We next assessed whether the top SNPs associated with HIV-1 amino acids represent indirect markers of HLA class I alleles known to exert evolutionary pressure on HIV-1 (Table 1).
Simulations and real data analyses results support the improved power of our PLS-based MLAS in disease genes mapping relative to other three MLAS approaches investigated in this study.
The improved power of the new models is even more pronounced when looking at estimates of the variance of divergence times (D T ) across the simulations.
This gradient is small but well defined and is perhaps an example of improved power of detection of such small effects for a common cancer.
If these tools become available for this population, it will be interesting to see whether the improved power of these studies allows the detection of more subtle effects such as interactions with environment or age.
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All of these methods were shown to have the ability to improve power of detecting the association assuming that the prior information was correctly specified.
First, it improves power of statistical analysis by increasing the sample size.
Our results point to the potential to improve power of detecting X-linked associations in the presence of variance heterogeneity.
In particular, whole genome sequencing enables the generation of better reference panels to improve imputation quality and thus improve power of subsequent association studies.
This case may be of practical use under certain circumstances, as it maximizes the number of independent measurements, thus improving power of subsequent statistical tests.
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