Sentence examples for improved mutations and from inspiring English sources

Additivity implies simple continuing fixing of improved mutations, and follows from a model in which selection in natural evolution quite badly disfavours lower fitnesses, a circumstance known from Gillespie as 'strong selection, weak mutation' (SSWM, see also ref. 224 229).

Finally, we finally applied this method to DNA derived from a tumor sample and demonstrated improved mutation detection accuracy.

None of the further modified position 16-based shRNA sequences showed either significant knockdown or improved mutation-specific selectivity (Figure S2B), and therefore further analysis of only the most efficacious shR-P16 construct was undertaken.

While improved mutation detection protocols can now identify JAG1 mutations in approximately 94% of patients diagnosed with Alagille syndrome [21], there are still some Alagille syndrome patients in whom no JAG1 mutations can be identified.

We believe these issues can be addressed by developing methods for co-reference resolution of mutation mentions and by improving mutation extraction and grounding algorithms, as well as extending gazetteers containing words describing directionality.

Future studies will focus on determining the role of merlin in tumorigenesis, improving mutation detection rates, and designing clinical trials for affected individuals.

Inclusion of flanking recombinase target sites and expression of the corresponding recombinase can enable recycling of markers and improve mutation stability, but this mandates additional steps and leaves a scar sequence at the target site.

Therefore, sequencing broader and deeper will likely improve mutation detection rates.

A simple, specific, comprehensive, reproducible, and reliable platform is important to improve mutation detection rates.

In collaborative mutation, end-point mutation and routing mutation are adopted collaboratively so as to improve mutation space.

We replaced regular PCR with SPACE-PCR before sequencing or genotyping assays to improve mutation detection sensitivity by up to 100-fold in detecting EGFR and KRAS somatic mutations.