In AD-model rats, produced by infusion of A β1-40 inthethe cerebral ventricle, DHA also improved learning ability [ 114].
For example, conditions that improve learning abilities in the water maze, such as enriched environments or middle-age adrenalectomy, also enhance neurogenesis [5], [6].
In human medicine, the inclusion of plentiful DHA in the diet is considered to improve learning ability and the development of the brain[ 11].
Future studies could test whether this is the case by electrically or optically stimulating neurons so that their activity synchronizes with the local population activity, and investigating whether this manipulation improves learning ability.
Exogenous injection of recombinant soluble neprilysin reduced Aβ levels and improved learning and memory ability of AD mice [ 31].
Our results firstly demonstrated improved learning and memory ability under the treatment of atorvastatin, using AD rat models.
Benefits included increased speed and accuracy of attention and visual special abilities improved learning and memory, executive functions, problem-solving skills and creativity.
By enhancing brain tissue hypoxia tolerance, chrysophanol was validated to protect neuron damage and improve learning and memory abilities [ 44, 45].
MesoHAP-OLZ can also improve learning and memory ability in rats with induced depression during Morris water maze (MWM) test.
Although CDS can improve learning and memory ability in Aβ25 35-induced Aβ25 35-inducedechADismodelremaitsd to be further determechanism
