Final analysis in the KRAS-WT population (n=597, or 55%) demonstrated a significantly improved median PFS with the addition of panitumumab to FOLFIRI (6.7 vs 4.9 months, HR 0.82, 95% CI 0.69 0.97, P=0.023), improved ORR (36% vs 10%, P<0.0001), and a non-significant trend toward improved OS in favor of the panitumumab arm (14.5 vs 12.5 months, HR 0.92, P=0.37).
A recent meta-analysis [70], including 7 RCTs and 10 observational studies, reported that there was a mild trend toward improved survival in favor of SLED-treated patients with AKI (RR 0.86; 95% CI 0.74 1.00), although the evidence was weak because of a lack of significant differences when RCTs were considered separately.
They found a strong trend toward reduced pain and improved function in favor of scapular taping at two weeks.
The regulators worry that Oracle may stop improving MySQL in favor of protecting its core traditional products, and customers will lose an important option in the database market.
The spread, or difference, between what high-cap borrowers pay and what small-cap borrowers are charged is improving sharply in favor of small-cap firms.
Yet the chemical industry has effectively lobbied against legislation that would require plants to improve security in favor of what is essentially self-regulation, and D.H.S. has accepted that.
Thus drug cocktails VPA/Li2CO3/LY2157299 or VPA/Li2CO3/Tranilast could significantly improve cell reprogramming, which was even better in favor of extracellular matrix.
Two GEP models have been developed, and the prediction uncertainties of the developed GEP models are quantified and compared with those of existing models, showing improved prediction accuracy in favor of GEP models.
HbA1c improved by 0.4% in favor of the intervention group, but within the intervention group, HbA1c was 0.5% lower in patients using CGM ≥70% of the time compared with <70% use.
12, 13 Years later, once these early visions had begun to be put in practice and genome exploration techniques had tremendously improved, efforts emerged in favor of the P4 principle: predictive, preventive, personalized, and participatory medicine.
