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Among the improved GO terms, "ion transport", "Golgi vesicle transport", and "vesicle-mediated transport" are cellular location specific GO terms, and these terms are only listed in this table.
Among the improved GO terms, "cell wall organization and biogenesis", "cell budding", "reproduction", and "external encapsulating structure organization and biogenesis" might be related to phenotypes of a cell, and only listed in this table.
We next provide finer and more precise functional annotations (i.e. improved GO depth) by curating literature.
An improved GO annotation for the A. niger CBS513.88 was applied that is based on ontology mappings from A.nidulans FGSCA4 (http://www.broadinstitute.org/fetgoat/index.html) [ 29].
We used the recently published improved GO annotation tool for A. niger (Fisher's exact test Gene Ontology annotation tool, FetGOat [ 29]), an open source tool accessible at http://www.broadinstitute.org/fetgoat/index.html.html
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