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These optimizations significantly improved domain decomposition performance.
Domains are the basic units of protein function and evolution; thus, improved homology detection requires improved domain alignment accuracy.
Establishing homology is central to a wide array of bioinformatics methodologies; improved domain alignments can improve 3D protein structural predictions that use homology modeling, and also clarify how protein domain networks interact to generate disease phenotypes.
This study provides information about the structure activity relationships that could be utilized for designing new inhibitors with improved domain selectivity for sACE.
Yeast display libraries of random and site-directed hVβ2.1 mutants were selected for improved domain stability and for higher affinity binding to TSST-1.
A modification to the algorithm for improved domain connectivity solutions in problems with tight tolerances as well as heterogeneous grid clustering is also presented.
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The post hoc analyses of the significant within-subjects effects of Time enabled a comparison of the improved domains within the two intervention groups, but no direct comparison could be made, and therefore no conclusion can be drawn about the relative strengths of the effects of the interventions for these domains.
The work of this research is mainly that adopt the combination of two ontology acquisition means to improve domain knowledge acquisition and propose a new semantic retrieval method to improve semantic understanding of case retrieval.
On-going curation to improve representation of some domain families and other efforts such as reported here to improve domain annotation consistency will reduce the fraction of sequences with incomplete DAs and hence the number of rare or unusual DAs in CDART.
The intervention study aimed to improve domain-specific knowledge and metacognitive awareness during online information problem solving (IPS) as part of an online inquiry project.
The curation of conflicting mappings in PPDMs is ongoing and we are hopeful that PPDMs can engage the community in reviewing and improving domain-level annotations of small molecule bioactivities.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com