Sentence examples for improved derivatives from inspiring English sources

Tryptanthrin, BII, and improved derivatives thereof have not been distributed on a commercial scale for application as antibacterial agents, and thus, they might represent attractive scaffolds for developing new antibacterials.

Improved derivatives of collagelin should be developed by further increasing the affinity of the molecule for collagen, and improving the labeling procedures.

To our knowledge, these sdAb represent the first recombinant antibodies specific for BoNT serotypes other than A, B or E [70], [71], [72], [73] and we hope these and future improved derivatives will facilitate increased biosecurity.

Cidofovir displays significant nephrotoxicity and limited bioavailability, and this has prompted the development of improved derivatives.

Optimization of its pharmaceutical properties could provide improved derivatives with greater benefit to breast cancer patients.

For the identification of potential metabolic "soft spots" and the rational design of improved derivatives, early biotransformation of a potent arylaminoethyl amide cathepsin K inhibitor (NVP-AAV490-NX) was investigated in plasma, urine and liver homogenates of rats after intravenous bolus administration of 10 mg/kg.

SLAC is a heavily modified and improved derivative of the Suzuki-Gojobori counting approach [ 42, 93] that maps changes in the phylogeny to estimate selection on a site-by-site basis.

Still, important progress has been made, notably in setting up the Consumer Financial Protection Bureau and bringing greater transparency to derivatives trading (including work to improve derivatives markets begun at the New York Fed under Timothy Geithner before he became Treasury secretary in early 2009).

Improving derivatives market regulatory systems and working towards international derivatives regulatory standards will be vital in achieving this goal but efforts to curb speculation so far have been lacklustre," says the report, which is called Macroeconomic impacts of oil price volatility: mitigation and resilience, and is published in Frontiers of Energy.

By combining rtTA2-M2 and an improved Dox derivative, 9TB-Dox, we have provided strong evidence for fast and robust gene activation in neurons when episomal Ptetbi modules had been introduced into the brain of our rtTA2-M2CaMK-2 mice (live GFP fluorescence, Fig. 4A).

This revealed the mechanism of APY-mediated antagonism and enabled rational design of an improved APY derivative.