Studies of the sedimentary architecture and characteristics of the Antarctic continental margin provide clues about past ice sheet advance retreat cycles and help improve constraints for paleo-ice dynamic models since early glacial periods.
For the presence of anelastic attenuation and anisotropic symmetries, these relations may provide improved constraints on thermal/compositional structure and deformational processes in the interior of Earth.
The testing apparatus designed involves a pin-joint between a loading frame and a testing fixture for improved constraint conditions and a cross-type specimens spot welded using guide plates in order to assure the constant ratio of the shear load to the axial load preventing a spot weld from rotating during the test.
Additionally, the construction of iCM925 highlighted important areas of investigation for future model-building efforts in other lesser-characterized microorganisms (e.g., genome annotation agreement), and for improved constraint-based simulation of non-growth phenotypes (e.g., alternative objective functions).
> -wrap-foot> The last part of this study involves evaluating the use of MetaPSICOV contact constraints for improving de novo protein structure models.
The use of SHAPE data driven soft constraints leads to improved prediction results for many RNAs.
The weak symmetry constraints and evolving symmetry experiments have significantly improved performance for the given task, although the evolving symmetry runs yield a relatively large variance in quality.
It is likely that performance could be improved by adding constraints to this model, for example, by leveraging haplotype identity among founder strains to reduce the number of states required at each SNP or by modeling heterozygous genotypes in terms of the homozygous state intensities.
After preprocessing we transformed the problem into 28 constraints for 34 variables, which dramatically improved the computational performance (data not shown).
For instance, the estimation of v4 – whose measurement was quite unreliable a priori – has been significantly improved, once model constraints and other measurements have been incorporated.
