Sentence examples for improved compounds from inspiring English sources

They may not be perfect, Dr. Cohen said, but if the drugs work even slightly in people, researchers can go to the chemistry lab and make improved compounds "This disease has a grapevine that is amazing," Dr. Miller said.

A better understanding of the structural chemistry of DOT1L inhibition would accelerate the development of improved compounds.

A quantitative structure-activity relationship (QSAR) study indicated that logS might be a key feature of the improved compounds.

Topotecan and irinotecan are chemically unstable and large efforts are being made to develop improved compounds [32].

Evolution of the initial hits led to improved compounds that behave as nonessential activators effecting both KM and Vmax values (Vmax=maximum rate of reaction).

The exploitation of surface transporters peculiar to trypanosomes is a straightforward way to specifically target fluorophores to these parasites, and improved compounds may be developed following this approach to target both human and animal infective trypanosomes.

The nanocomposites were prepared via solution blending from tetrahydrofuran utilizing a three-roll mill for improved compounding.

No doubt the use of better instruments (i.e. faster scanning quadrupoles or TOF instruments with greater sensitivity), multiple extraction steps or the use of different derivatization steps could have improved compound coverage.

Moreover, improved compound potency corresponded to a much higher degree of predicted fit within the allosteric site compared with rimantadine.

Several hurdles still need to be overcome, including improved compound specificity and the importance of many key pathways for homeostasis and host defense [ 37].

This improved compound was used to probe the C-terminal (R2, 35) position and was shown to improve in vivo potency in an HSV-1 induced keratitis mouse model.