Exact(2)
It has displayed increased binding affinity and a longer dissociation time when compared to rituximab resulting in improved complement dependent cellular cytotoxicity (CDCC); a mechanism with the potential to overcome apoptosis-resistance in TP53 disruption.
A thorough knowledge of its structural and dynamical properties in solution may assist the design of improved complement inhibitors.
Similar(58)
These regulatory proteins are expressed on NPA cell membrane and probably partially protect them from CDC. Combining the various human recombinants anti-TPO aAbs we selected by phage display and characterised in term of epitopes (Bresson et al, 2003, 2004; Chapal et al, 2000; Rebuffat et al, 2006), could make it possible to improve complement activation.
Furthermore, Hsu [11, 12] improved and complemented the main results obtained in [10].
His results improved and complemented the corresponding results of Marino and Xu [13].
His result also improved and complemented the corresponding results of Cho et al. [5], Jung [6], Marino and Xu [13] and Tian [15].
The system described in this article has in major ways improved and complemented these previous sources of information.
The structuring of conservation policies around the protection of rare species and habitats, as well as pristine sites, could also be improved or complemented.
These results improve and complement a number of earlier works.
We improve and complement previous results in the literature.
The results obtained essentially improve and complement earlier ones.
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