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The Whistler ski area was markedly bigger, better and greatly improved by the advent of the Peak 2 Peak gondola: previously skiers had to descend to the lift base to switch between the two mountains.
The accuracy has since been improved by the advent of the multislice technique (MSCT).
Outcomes for patients with DLBCL have been significantly improved by the advent of rituximab; 1, 2, 3, 4, 5, 6, 7 however, a certain percentage of patients still show insufficient response to this therapy and die of the disease.
Follow-up of DTC was greatly improved by the advent of Tg measurement in the early 1980s and, due to the gradual improvements in the sensitivity and precision of Tg assays (9), the combination of Tg measurement and neck US is now regarded as the de facto standard of care (2, 3).
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The success of organ transplantation has greatly improved since the advent of the immunosuppressive drug cyclosporine.
The outcome of patients with mRCC has been improved since the advent of targeted therapy.
Outcomes have improved with the advent of craniofacial resections.
The performance of forensic analysis with degraded DNA has also improved with the advent of PPY23.
While outcomes have improved with the advent of new therapies, further progress is needed.
Survival has greatly improved with the advent of HAART in children.
Fortunately, this situation has recently improved with the advent of vasopressin receptor antagonists (also known as 'vaptans'; see below).
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