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In fact, in some cases, we observed improved bone measures associated with TCDD exposure.
Future studies will also be needed to understand whether BML regression eventually leads to improved bone measures and decreased risk of osteoarthritis progression over the long term (for example, cartilage loss, joint-space narrowing).
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In a pilot study in seven haemodialysis patients, use of teriparitide improved bone mineral density measured with DEXA [ 4].
In a recent trial exploring the effects of HRT in RA, we found ameliorating effects on clinical measures of disease activity and inflammation, improved bone mineral density (BMD), and also results pointing towards retardation of joint damage [ 11].
In surgical disciplines, where bones have to be repaired, augmented or improved, bone substitutes are essential.
12, 42 In murine models, denosumab improved bone density and bone volume and reduced bone resorption.
Our data provides initial evidence of improved bone regeneration after graft augmentation of metaphyseal bone defects.
Additionally, decreases in markers of bone metabolism were associated with improved bone mass.
Together, both doses of odanacatib increased bone mass and improved bone strength at the hip.
Second, to identify if adjunct aripiprazole will improve bone turnover as measured by assays of osteoblastic and osteoclastic activity.
It is well known that Mg ion improved bone-like apatite nucleation and growth.
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