Sentence examples for improved affinity with from inspiring English sources
However, AF-71 and AF-80 have improved affinity with M2 compared to that of wild type.
Bacterial cell surface hydrophobicity is one of the most significant features that determines bacterial adhesion to an oil water interface, which can accelerate cell transfer to the water oil interface due to an improved affinity with oil and strengthen the aggregation of dispersed droplets in the W/O emulsion (Liu et al. 2011a, b).
The variant DigA16/19, which carries several new mutations, exhibits clearly improved affinity for digoxigenin, with KD=12.4 nM.
Both mutants showed improved affinity toward NADH (with the KM, NADH decreased ~2 times in the case of H220N and ~3.5 for H220Q), and the kcat, NADH of H220N was slightly increased.
In contrast, constructs A1B2, A1B2D1W and A1B2D1R displayed binding properties with improved affinity for 5-HT3R ligands.
A single-chain Fv fragment (scFv) against estradiol-17β (E2) was generated to begin the construction of a library of various mutated anti-steroid antibodies with an improved affinity and/or specificity.
Based on the DOTAGA chelator and the use of a d-amino acid spacer, compound 12 possesses remarkable potential for a PSMA based theranostics concept and is a suitable lead structure for the continuing development of PSMA ligands with further improved affinity.
Remarkably, the N367I mutation completely abolishes D-glucose uptake and allows D-xylose uptake with an improved affinity.
Two modified proteins with greatly improved affinity for xyloglucan, a key polysaccharide abundant in the plant kingdom crucial for providing plant support, were generated.
The main strengths of the concept are that a small set of polypeptides can be used to develop binder molecules for any protein by conjugation to small molecules or peptides with only modest binding capacities, and that the binder molecules target the proteins that the small molecules recognise but with much improved affinity and selectivity.
With compound 1b, a new ligand with a twofold improved affinity to the best so far known d-GalNAc was identified.
