Sentence examples for improved activity against from inspiring English sources
Some derivatives exhibited greatly improved activity against erythromycin-resistant bacteria.
Although several new antibiotics were developed in the last few decades, none have improved activity against multidrug-resistant bacteria [7].
Compound 7c exhibited improved activity against erythromycin-resistant S. pneumoniae encoded by the erm and mef genes.
These benzimidazolyl derivatives exhibited excellent activity against erythromycin-susceptible strains better than the references, and some of them showed greatly improved activity against erythromycin-resistant strains.
These derivatives had excellent activity against erythromycin-susceptible Streptococcus pneumoniae, Streptococcus aureus or Streptococcus pyogenes and some of them exhibited greatly improved activity against erythromycin-resistant strains.
The 4″-carbamate analogs retained excellent activity against erythromycin-susceptible Staphylococcus pneumoniae and showed improved activity against erythromycin-resistant Staphylococcus pneumoniae.
As observed for the methyl addition, the addition of the ethyl group did not significantly improve activity against most organisms; however, a slight but consistent 2-dilution improvement was observed in the activity against S. pneumoniae, which suggests an advantage to having combinations of alkyl groups more than 2 carbons.
A class of sulfonamide-substituted diphenylpyrimidines (Sul-DPPYs) were synthesized to improve activity against the focal adhesion kinase (FAK).
Azithromycin has shown potential in malaria treatment so we designed hybrid azalide molecules with the aim to improve activity against and selectivity for the malaria parasite.
The antimicrobial activities of CFX are mainly achieved through the chlorine-substituted N 1 cyclopropyl group which enhances cell penetration and improves activity against DNA gyrase and topoisomerase IV enzymes [20].
The thieno[3,2-c]pyrrolidone unit was more suited for improving activity against Aspergillus spp. The most potent compound, 18a, was selected for further development due to its significant in vitro activity against Aspergillus spp. (MIC = 0.25 μg/ml), as well as its high metabolic stability in human liver microsomes.
