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The findings, published in the journal Alzheimer's & Dementia, will be used to improve trials for new dementia drugs.
We also review regulatory guidelines for end points and trial design and recommend ways to improve trials.
Serum biomarkers predictive of disease state will improve trials for therapeutic intervention, and disease monitoring, particularly in genetically susceptible individuals.
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Overall, the results of recent lupus trials challenge the rheumatology community to improve trial approaches in SLE, a patient population in need of improved therapies.
The following year, the State Legislature passed a law intended to improve trial representation for poor defendants in all criminal cases.
However, Touraine announced measures to improve trial safety in the future.
This approach may improve trial design and implementation of tailored therapies in genetically and clinically complex autoimmune diseases.
In recent years, advances in Alzheimer's disease (AD) biomarker research have provided powerful tools to improve trial design.
Insight into possible reasons for non-participation could help to improve trial designs and participation rates among this age-group.
Subgrouping patients on the basis of individual sensory profiles could reduce this heterogeneity and improve trial design.
Qualitative research may be conducted concurrently with pilot or full RCTs to understand the feasibility and acceptability of the interventions being tested, or to improve trial conduct.
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CEO of Professional Science Editing for Scientists @ prosciediting.com