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Other studies reported that HA did not change the progression of osteophytosis or fibrosis and did not improve the progression in knee articular disease46,47,48,49.
The authors showed that a distributed network could improve the progression of CKD in patients with stage 3 5 CKD comparatively to usual care.
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Cediranib, in addition to cisplatin/gemcitabine [CisGem], improved the response rate, but did not improve the progression-free survival (PFS) in the ABC-03 study.
Sequential inhibition of the MAPK pathway by combination therapy with dabrafenib (a selective BRAF inhibitor) and trametinib (MEK inhibitor) has been shown to improve the progression-free survival in patients with BRAF V600 melanoma (Fig. 6b and c) [43].
Together our results suggest the hypothesis that Chk1 inhibition might improve the progression-free survival of NSCLC patients during chemotherapy treatment.
The study is designed to demonstrate that a carbon ion boost in combination with postoperative photon radiotherapy can improve the progression-free survival rate after 3 years (PFS-3yR) by 20%.
We designed arm C CCRT + CT) to examine whether the addition of consolidation chemotherapy to CCRT could improve the progression-free survival and overall survival in patients with intermediate-risk factors after radical surgery.
This observation implies that repeated blockage of ETAR improves the progression of the development of neuropathic pain.
Inhibition of the VEGF receptors (VEGFRs) by small tyrosine kinase inhibitors (TKIs), such as sunitinib that was the first TKI approved for advanced RCC, markedly improved the progression-free survival (PFS) and the overall clinical outcome of these patients (Schoffski et al, 2006; Faivre et al, 2006a).
Although the recent chemotherapeutic regimens have improved the progression-free survival and overall survival of advanced gastric cancer patients, the median survival time is often less than 1 year and none of the regimens has yet emerged as a clear standard (Ref. 7).
We perform both mouse and human experiments hoping to identify quantifiable phenotypes correlated with genotype and in a second step evaluate whether this assay could be used to discover novel drugs improve the disease progression.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com