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It is natural, they said, to try to improve the potency of the tracking systems by integrating data from online and offline sources.
An obvious future direction is to improve the potency of these compounds against wild-type yeast.
Placement of a primary or secondary carbamate at C6 did not improve the potency of compounds toward inhibition of MetAP2.
To improve the potency of vaccines, immunostimulants targeting these PRRs are often used as adjuvants to activate and prepare the immune system for reacting to specific antigens.
However, increasing the hydrophobicity of the two clusters using non-natural amino acids did not significantly improve the potency of the peptides.
The promising results obtained in this study make these compounds valid leads for further optimization studies aiming to improve the potency of this new class of kallikrein inhibitors.
Similar(5)
New delivery technique including DNA transfer by electroporation recently greatly improved the potency of this concept.
Further substitution of Lys2 with Nle slightly improved the potency of the tetrapeptide, which selectively activates FPRL1 over FPR.
Discovery of the novel scaffolds and binding mechanism suggests avenues for extending the interaction surface and improving the potency of a hydrophobic pocket binding inhibitor.
The pharmacological results suggest that the substituent groups are vital for improving the potency and selectivity of this class of compounds.
Although DNA immunogens have been shown to stimulate both the cellular and/or humoral arms of the immune system, improving the potency of these vaccines is clearly important.
More suggestions(17)
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com