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Large, international collaborative efforts at designing and conducting studies to optimize treatment options for patients with ErbB2-positive breast cancer are ongoing, and careful review of data from these trials will improve tailoring of these modern therapeutic strategies.
Gaining understanding in moderating factors is important as it might help to improve tailoring interventions to children.
Accordingly, we can now derive an adequate precising definition of PM: PM seeks to improve tailoring and timing of preventive and therapeutic measures by utilizing biological information and biomarkers on the level of molecular disease pathways, genetics, proteomics as well as metabolomics.
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Larger case-studies will be necessary to deepen investigation on the prognostic and predictive role of such markers in patients with stage II colon cancers, also adopting a multisegmental approach to bowel subsites [ 55] in order to improve tailored preventive and therapeutic strategies.
This improved tailored support would include the development of funding models that provide long term commitments and support to enable them to develop their research skills.
Thus, undertreatment of stage I and II patients as well as overtreatment of stage III patients may be avoided, improving tailored adjuvant treatment and follow-up.
Additionally, improvements in choices of treatment are themselves implied by improved tailoring of treatment.
Third, our definition contains "improving tailoring of prevention and therapy" as one end of PM.
This allows improved tailoring of treatment both in the adjuvant and the preventive setting [ 4, 5, 17].
More specifically, the discourse seems to focus on tailoring therapeutic interventions to a patient's specific characteristics: about 25% of all ends collected refer to (improved) tailoring of therapeutic interventions.
Improved tailoring of treatment for BC requires integration of clinical pathologic and cancer biological information to ensure all known variables that could potentially influence patient outcome and response to therapeutic treatments are considered.
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