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Therefore, it is very necessary to develop new therapeutic strategies that could enhance CIK therapeutic effects and/or improve synergistic combined therapy.
These GH43 family members contain β-xylosidases and α-arabinofuranosidases; the CBM6 regions may improve synergistic interactions of the GH43 enzymes with the endo-hemicellulases for degradation of insoluble substrates.
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Furthermore, NPbig&small demonstrate well EPR effect and improved synergistic efficacy from in vitro and in vivo results.
A remarkably improved synergistic therapeutic effect to pancreatic (PANC-1) tumor-bearing mice was obtained compared to the result of chemotherapy or PTT alone.
Despite the successes application of HIFU, however, the optimization of HIFU treatment is still challenging for improving synergistic effects of nanoparticle-based drug delivery systems due to irreversible thermal effect, including hemostasis and blood vessel occlusion.
In addition, active oxygen species indicated by the O 1 s XPS spectrum and improved synergistic effect between NiO and Co3O4 reflected by H2-TPR, further explain the enhanced performance of the HLDO catalysts.
Using a combination of random mutagenesis and DNA shuffling, we have isolated several Tx-Xyn variants that showed increased activity on wheat straw and improved synergistic action, when used in combination with a commercial cellulase preparation.
The adding of alkali will improve the synergistic effects between betaines and fractions in general by enhancing the adsorption of fractions and producing soaps.
To improve survival, synergistic combinations would be also interesting.
To improve the synergistic effects, a combination of docetaxel, estramustine, and low-dose hydrocortisone has been trialed; unfortunately, 50% of men with CRPC acquired resistance toward treatments [ 135].
Generally, the performance of OER catalysts can be significantly improved by synergistic action of the underlying conductive substrate.
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