Moreover, in order to improve specificity, targeting photosensitizers specifically to a certain type of microorganisms was tested.
To improve specificity, probes were designed over gene-specific variants, to distinguish between homologous pseudogenes and the actual gene regions of PMS2 and CHEK2.
Delivery systems can improve specificity of cancer cell targeting, prevent non-specific delivery of siRNA, and may also protect the siRNA during transport.
Future improvements will include the incorporation of targeted imaging contrast agents to improve specificity for imaging tumours.
Importantly, CD146 by itself is neither a sensitive nor a specific marker of Th17 cells, and combinations with other markers, at best, improve specificity but reduce sensitivity.
Detection of HPV mRNA may improve specificity.
To improve specificity, adjunctive technologies have been developed to identify fetuses at risk for intrapartum asphyxia.
More recently, inhibitor design has considered secondary binding sites (exosites) to improve specificity.
To discuss how we might improve specificity in precision medicine, we will concentrate on issues concerning tumor heterogeneity.
Dynamic-contrast enhanced (DCE) MRI and DWI are functional sequences that improve specificity [20, 24, 28, 31].
Additionally, in order to improve specificity, more samples could be detected to set a more exact threshold.
