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Since higher levels of hippocampal neurogenesis are typically associated with improved cognitive function11,12, in what way might neurogenesis-mediated clearance improve memory function?
Studies have shown that administering specific nutrients may improve memory function, possibly by increasing synapse formation.
The findings, published in the April issue of Nature Neuroscience, might lead to new drugs to improve memory function in amnesia and neurodegenerative diseases.
I head a diverse team of researchers that study these neurobiological mechanisms in rats, mice, and humans, and lead a series of studies to test treatments in animals as well as a clinical trial in humans designed to improve memory function in older adults who suffer from memory problems such as patients with mild cognitive impairment who are at risk for Alzheimer's disease.
For instance, factors that increase adult neurogenesis, such as environmental enrichment (EE) and exercise, improve memory function (for review, see [16], [17]), whereas a reduction of neurogenesis induced by stress results in memory impairment [18], [19].
17 Another evidence-based review showed that errorless learning training programs could improve memory function in patients with dementia.
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Our study provides evidence that a relatively short intervention can improve memory functioning in patients with epilepsy.
A few studies have suggested that cholinomimetics or AChE inhibitors can improve memory functions not only in Alzheimer's disease but also in other pathologies.
In the previous study, we showed that the ethanolic extracts of Radix Puerariae (RPE) and its prime constituent, puerarin induced neuritogenesis and synapse formation in cultured hippocampal neurons, and thus could improve memory functions.
Studies have found that spending time in nature can help improve memory functions – especially short-term memory.
5 In a randomized placebo-controlled trial examining the effect of memory training, findings suggested that a six-week training on categorization and visualization techniques failed to improve memory functioning in a group of probable AD patients.
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