Your English writing platform
Discover LudwigExact(5)
These results successfully validate that SiMBR can effectively improve flux through direct reduction of biomass concentration.
A number of strategies were implemented to improve flux through the pathway, including enzyme variant screening, genetic copy number variation, and culture optimization, that led to an over 70-fold increase in canadine titer up to 1.8 mg/L.
For instance, disruption of ethanol synthesis has been demonstrated to substantially improve flux through the 1, 3-PD biosynthetic pathway in K. pneumoniae (Zhang et al. 2006).
An initial attempt to improve flux through the mevalonate pathway was made by re-synthesizing the MevT operon, which expresses the first three genes of the mevalonate pathway, with genes codon-optimized for expression in E. coli.
Addition of xylose may improve flux through the pentose phosphate pathway, increasing the ability of S. cerevisiae to utilize gluconic acid.
Similar(55)
Specifically, two different model objectives were used to identify possible genotypes that exhibited either improved overall NADPH production or an improved flux through an artificial reaction coupling NADPH yield to biomass.
In the heterozygous state it is suggested that they would relax their control of metabolism and growth processes, resulting in improved flux through biochemical pathways.
Changing the 'anabolic' codon usage of valine synthesis genes into a 'catabolic' codon usage further improved flux through the new pathway.
Here, we describe a framework which uses a combination of computational modeling techniques to design an in silico metabolic engineering strategy that improves the flux through the aromatic amino acid pathway (shikimate pathway) in S. cerevisiae.
The results suggest that codon-optimization clearly improved the flux through the new cytosolic valine pathway.
Most studies have focused on the MVA pathway and on improving the flux through it both in natural hosts as in heterologous hosts.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com