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Nebulization of anticoagulants may allow for improved local biological availability and as such may improve efficacy in the lungs and lower the risk of systemic bleeding complications.
To evaluate a combination of oral misoprostol (OM) and mechanical dilation of the cervix to improve efficacy in inducing labour.
Combining the β3-adrenoceptor agonist mirabegron and the antimuscarinic (AM) agent solifenacin may improve efficacy in the treatment of overactive bladder (OAB) while reducing the AM side effects.
This delivery system is favorable to overcome the shortages of biopesticides, such as environmental sensitivity, poor water solubility, and hence improve efficacy in crops protection, decreased the spraying dosage, and reduce residues and pollution in food and environment.
Seasonal targeting of IPT given only to infants does not improve efficacy in sites with completely uniform transmission over the whole year, as would be expected (table 3).
It is to be hoped that the addition of targeted agents to FOLFOX might further improve efficacy in this setting.
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Moreover, the compound has improved efficacy in a hedgehog/smoothened signaling mouse pharmacodynamic model.
This might provide improved efficacy in the lung whereas the systemic side effects would be primarily driven by free drug concentrations in plasma.
A variety of magnetic nanomaterials has been developed to achieve improved efficacy in cancer therapy as well as reduced side effects compared to conventional therapies.
Compared with analgesic medication alone, combinations of caffeine with analgesic medications, including acetaminophen, acetylsalicylic acid, and ibuprofen, showed significantly improved efficacy in the treatment of patients with TTH or migraine, with favorable tolerability in the vast majority of patients.
The α-asarone-LE not only showed a desired stability, but also exhibited excellent safety and improved efficacy in vivo, indicating its great potential for clinical application in the future.
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