Sentence examples for improper target from inspiring English sources

Exact(1)

Toxicity of RNAi can occur through improper target recognition resulting from suboptimal annealing of the antisense guide strand to the target strand, improper selection of an unintended passenger strand by the RISC complex, or overloading of the silencing machinery.

Similar(59)

The document also demanded the identity "by name, grade and position title" of "every I.R.S. supervisor, I.R.S. manager or other I.R.S. employee who became aware that any individual in the White House or Treasury Department became aware of any improper targeting".

Among other things, the committee asked for documents between I.R.S. employees "and anyone else" about targeting groups by certain phrases as well as documents showing communications with the White House about the targeting, and the identity of every I.R.S. employee "who became aware that any individual in the White House or Treasury Department became aware of any improper targeting".

Now, as the White House grapples with questions about what it knew about the improper targeting of Tea Party groups by the Internal Revenue Service and growing anger over the Justice Department's seizure of journalists' phone records, some top Republican strategists say they are still incorporating the lessons of 2012.

Small molecule-based regimens inhibiting over-expressing Hsp90 in cancer cells often plagued with improper targeting leading to non-specific toxicity.

"A penalty of ten points will be imposed against a team if any member demonstrates an excessive use of marking rounds (fire control and intentional improper targeting of body parts, i.e., headshots)," reads the Urban Shield Exercise Plane.

Some would say we've entered a perfect storm already, given the numerous examples of improper targeting of domestic advocacy groups, most recently the FBI raids on various anti-war activists' offices and homes in Minneapolis and Chicago.

As the FBI's own inspector general explained in earlier criticism of the FBI's improper targeting these last few years of anti-war movements and the FBI's false justifications for doing so, the FBI sometimes simply needs to "make work" on a "slow day".

Yeast expressing our initial Fz1-Ura3p construct failed to grow in the absence of uracil (Fig. 2A, top), and we reasoned that this might be the result of improper targeting of the protein to the yeast secretory pathway.

From a clinical perspective, this overestimation may lead to improper targeting of preventive strategies because of the large number of patients with false-positive results who are identified for treatment.

Since improper targeting of pendrin was observed in almost all differentiated thyroid carcinomas and since pendrin mRNA and protein expression were comparable to noncancerous thyroid tissues, one may speculate that this is a general phenomenon of trafficking of pendrin in thyroid neoplasm.

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