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Any improper sensitivity of SNAP to polymorphisms should be of serious concern to those who wish to use gene predictions for subsequent experiments or genome analyses, especially given that SNAP was additionally sensitive to random polymorphisms that could result from random mutation or sequencing error.
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With only eligible studies included in the analysis and including the data from multi-arm study, and after correction of improper data, sensitivity analysis indicated that our result was stable and funnel plot and Egger's test indicated that there was no publication bias.
The factors include (in order of most significant): "self-interest, failure to maintain objectivity and independence, inappropriate professional judgment, lack of ethical sensitivity, improper leadership and ill-culture, failure to withstand advocacy threats, lack of competence, lack of organizational and peer support, and lack of professional body support".
Although it is possible that the low prevalence in healthy individuals might be attributable to other factors, including improper specimen collection or assay sensitivity, it is also possible that HPV may function to modulate the malignancy process in developing or established oropharyngeal tumors, as has been observed in studies of HPV infection in other developing cancers [ 29- 39].
Discontinuous error metrics such as proportion of misclassifications, sensitivity, and specificity are "improper scoring rules" however, since they impose arbitrary thresholds on predictor models and do not capture the uncertainty in the predictions [27].
However, improper constraint models might degrade the sensitivity and specificity of the motifs discovered by computational methods.
(Registered allopathic doctor no. 3, MBBS, 2 years experience) According to the interviewees, there was a lack of good laboratories for culturing and sensitivity testing, which caused improper diagnosis and hence irrational antibiotic prescribing in humans.
The η on ξ, ξ on η and major axis methods give an improper SROC curve if and only if sensitivity and specificity are positively correlated.
All other connections were considered for our revised model space, reducing the bias of an improper a priori exclusion resulting from potential sensitivity constraints in the first-level analysis.
Embryonic neurons lacking Drp1 show improper mitochondrial distribution consistent with Figure 1 and increased sensitivity to apoptosis.
But the two lists included in the memorandum written in 2000 show that quality control problems with foam were among the most pressing issues and cite "material deficiency" and "improper application" of foam, including a "lack of understanding of sensitivity of foam performance to changes in foam processing, material component changes and environments".
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