Sentence examples for imprint established from inspiring English sources

Xist expression patterns in the reconstructed embryos suggested that the nature of imprinted XCI is the maternal Xist-repressing imprint established at the last stage of oogenesis.

The imprint established by the original virus infection governs the antibody response thereafter.

This observation suggests that the maternally inherited mini-X-chromosome carries an imprint established in the germline that interferes with the somatic spreading of heterochromatin silencing in the next generation.

You can't be 'mostly independent.'" Schnackenberg cites these new rules as the sort of thing that Umbrella – a voluntary organisation formed in the 1980s by labels Mute, 4AD, Beggars Banquet and Rough Trade – was set up to stop: "fake" indie imprints, established with major label involvement.

Thus, some genes may be more prone than others to stochastic methylation errors in sperm, e.g., by less stringent maintenance of the methylation imprints established in the male germline.

While transgenerational epigenetic inheritance remains controversial, at least in humans, 33 the phenomenon of genomic imprinting establishes the principle that epigenetic marks such as DNA methylation placed in one generation can influence gene expression in the next.

This could suggest a difference in the mechanism or developmental stage during which the two types of somatic imprint are established.

For H19, the imprint is established during the adult spermatogonial stage or at least before the spermatocytes enter meiosis I, and is maintained thereafter (Kerjean et al., 2000), resembling the reprogramming in the mouse (Ueda et al., 2000).

Understanding the molecular mechanisms by which imprinting is established in all mammals is critical to furthering knowledge about imprint gene regulation in humans.

As genomic materials of PG-haESC lines originated from mature oocytes, in which maternal imprints were established during oogenesis, we anticipated that PG-haESCs might maintain maternal imprints.

Oocyte-specific methylation imprints are established during oocyte growth concomitant with DNMT3A/DNMT3L expression, although the mechanisms of oocyte-specific imprinting are not fully understood.