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Meynell's trade books, published under the same imprint, demonstrated that well-designed and manufactured books need not be costly; the Nonesuch one-volume editions of English classical authors were inexpensive, handsome, and readable.
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Evidence from genetic analyses demonstrated that gene imprinting in the placenta is altered in pregnancy loss [ 10].
CDKN1C resides in synteny with IGF2, demonstrating that imprinting of the two genes did not occur concurrently to balance maternal and paternal influences on the growth of the placenta.
Mosaic fragments and imprints of tesserae in the vaults of baths and buildings of similar size demonstrate that mosaic gradually was introduced into new fields.
Our findings demonstrate that DNA sequence characteristics, including recombination hot spots, are sufficient to accurately predict the imprinting status of individual genes in the human genome.
By using the murine Gnas imprinted domain, he demonstrated that truncating the most upstream Nesp gene, which is transcribed through the whole locus in oocytes, including across the two germline differentially mehtylated regions (DMRs), disrupts methylation acquisition at the DMRs.
ICR1 epigenetic testing was designed to cover the CpG sites located at the sixth CTCF-binding site (Table S1) because we previously demonstrated that imprinting at this site is stable during development.
The requirement time experiment for olfactory imprinting clearly demonstrates that exposure to the test water for 14 days is enough to create an olfactory memory of the test water in the experimental fish in May.
This promoter presumably also uses alternative enhancers that are not blocked by insulator activity on the maternal allele, as H19 retains imprinted expression demonstrating that the initiator (insulator complex) is present [ 25].
We demonstrated that novel imprinted genes, such as FAM50B, as well as novel imprinted DMRs associated with known imprinted genes (for example, CDKN1C and RASGRF1) can be identified by using this approach.
As detailed above, in the revised version we have further validated allele-specific imprinting for four genes and demonstrated that the all of the TEs associated with allele-specific imprinted genes are present at the same genomic location in all three strains.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com