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The first meta-analysis on the acute and long-term effects lithium in unipolar depression found an "impressive effect" of lithium vs. placebo in RCTs over 5 months to 3 years and also in uncontrolled studies (Souza and Goodwin 1991).
Second, time effect: While early studies (published in 2005) show a very impressive effect of DES, later studies found less benefit for DES compared to BMS.
Perhaps the impressive effect of hygienic measures aimed at younger children is based on their poor capability of being hygienic.
Results of this study emphasize the modest effect of exercise, the necessity of coupling weight loss with exercise, and the impressive effect of combined treatment.
This concept may explain both the impressive effect of cytokine inhibitors in many RA patients as well as their failure in a subset of these patients.
If the impressive effect of sodium nitrite on reperfusion injury does translate from animal studies to humans, this would result in smaller infarcts and potentially better functional parameters in patients treated with nitrite.
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Arrangement and the worth of the burnable poisons (BPs) has an impressive effect on the main control parameters of a nuclear reactor.
We observed impressive effects of RYGB on diabetes even though our subjects had very severe diabetes.
These clinical results are far from the sometimes impressive effects of PEEP seen in experimental models.
In MCF-7 cells, the most impressive effects of bisphosphonates were observed with FGF-2 since all four bisphosphonates almost completely abolished the FGF-2 stimulatory effects (86 99% inhibition).
Despite a lack of effect on serum lipids, impressive effects on other important surrogate markers of cardiovascular risk were observed.
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