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Moreover, establishing a protocol to induce differentiation of hESCs into hematopoietic progenitors provides an easy approach to access to initial steps of hematopoiesis during human ontogeny, which occur in the first weeks of the developing embryo and are therefore impractical to study in vivo.
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It would be ideal, although clearly impractical, to study a younger, premenopausal group of women in order to eliminate these confounding factors.
Perhaps the greatest remaining limiting factor for in situ experiments is specimen thickness, which limits electron penetration, making it impractical to study specimens thicker than roughly 0.5 1.0 μm.
Generally, animal models are needed when it is impractical or unethical to study the target animal.
Substantial delays to travelers and ethical concerns such as follow-up treatment made it impractical to conduct this study in an airport setting.
Given the resource constraints, it is impractical to perform standard in-laboratory attended PSG for all patients in the POSA study.
Together, these clients allow researchers to study biomedical questions previously considered impractical to tackle computationally.
Using a long segment construct to study the biomechanics of implants is time consuming and impractical.
However, it is frequently impractical to perform studies on control subjects to obtain RVs.
This does not represent the complete CMV-specific T cell response, which could involve over 100 viral antigens [ 13]; however, this would be impractical to measure in a large cohort study such as ours.
While the most obvious mitigating intervention in response to network damage is the direct reversal of the damage, this may be impractical to implement in the system under study (for example, there may not exist a drug to target the deregulated protein).
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