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The N′-loop and L4 are both intrinsically disordered loops that lack intra-molecular interactions with other residues, and therefore, it is impractical to observe them in crystal structures.
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Writer went to Washington to observe them at work.
I mean you have to Observe them.
Our view is that latent 'crime topics' capture features of the behaviors and situations underlying crimes that are often impractical to observe and almost completely lost when adopting formal crime classifications.
Values for the six disease progression parameters described above (rd, xdu, ru, xds, rs, and σds) are impossible or impractical to observe, and their values can be expected to differ based on disease and patient characteristics of the groups of interest.
To find out, we observe them and we take them apart.
However, it is impractical to use them for twist optimization due to the high computational cost.
Because their motors are air-cooled, it is impractical to wrap them in sound-insulating material.
Although researchers have had new transducer designs in mind for years, it has been impractical to construct them subtractively.
"With about 75,000 people having named Ryan Giggs on Twitter, it's obviously impractical to imprison them all," Hemming said.
Then a close friend came over with her eight-year-old son, who insisted on swimming, and it just became impractical to stop them.
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