Since the various studies used different gene expression platforms, tumor selection criteria and isolation and labeling methods, it was impracticable to combine data from these studies with our data into one large dataset and perform a meta-analysis.
Since mate-pair sequencing libraries are costly and time-consuming to generate, it is generally impracticable to generate data for each FP using this approach.
In two studies it was impracticable to extract data on withdrawals and drop-outs relevant to AEs; one study 29 did not report the reason for withdrawals and another 32 did not mention the withdrawals and drop-outs at all.
This high volume of output is unnecessarily awkward for exome data and impracticable for whole genome data.
Models are a way of representing the complexity of the real world in a more simple and comprehensible form where true data are infeasible or impracticable to obtain.
The number of sub-matrices, S, (possible δ-biclusters) in an M × N matrix is: (2) S MN = (2 N - 1)(2 M - 1) In such an exponential search space an exhaustive search through all possible sub-matrix solutions is NP-hard [ 16] and therefore impracticable in large gene expression data matrices.
Direct measurement of biochemical parameters in vivo is often difficult and sometimes impracticable, while fitting them under data-poor conditions may result in biologically implausible values.
The fact is that assuming we have infinite computing resources for big data analytics is a thoroughly impracticable plan, the input and output ratio (e.g., return on investment) will need to be taken into account before an organization constructs the big data analytics center.
This approach is impracticable for modern datasets with increasing amount of data: on the one hand, projection and backprojection become costly operations, while on the other hand, even more iterations are required due to the higher number of variables.
However, when despite reasonable efforts—it would be impracticable to seek the individual's consent, the data may be gathered without the individual's explicit consent, provided that certain conditions are met.
Estimating the contribution of this conceivable effect to the correlations observed in microarray data is a difficult and probably impracticable task because the processes of cross-hybridization cannot be observed directly.
